Publications 

Goodson BA, Vazquez VM, Doyle A, Kolaczkowski OM, Liu R, Jia J, Ishida M, Ye C, Kell AM, Bradfute S, Lemus MR, Wang H, Han X, Pu J. SARS-CoV-2 ORF3a blocks lysosomal cholesterol egress by disrupting VPS39-regulated NPC2 trafficking and BMP metabolism. Cell Reports. 2026. PMID: 42287635.

LaPointe AT, Ferrara F, Zupancic JM, Montoya AL, Schmidt J, Hung LW, Kell AM, Velappan N. Discovering Novel Therapeutic V(H)Hs for Emerging Viruses: Perspectives from VEEV Selection Strategies. Front Immunol. 2026. PMID: 41659433.

LaPointe A, Martinez K, Shou C, Manuelyan I, Botten J, Kell AM. Specific and versatile monoclonal antibodies for hantavirus research. mSphere. 2025. PMID: 41288105

LaPointe A, Klimaj SD, Kell AM. Impact of Species and Cell-type on the RNA Replication Kinetics of Seoul Virus. Journal of General Virology. 2025. PMID: 41334986

Gonzalez V, Word C, Guerra-Pilaquinga N, Mazinani M, Fawcett S, Portfors C, Falzarano D, Kell AM, Jangra RK, Banerjee A, Seifert S, Letko M. Viral Suceptibility and innate immune competency of Carollia perspicillata bat cells produced for virological studies. PLoS Biology. 2025. PMID: 40233033

Klimaj SD, LaPointe A, Martinez K, Acosta EH, Kell AM. Seoul orthohantavirus evades innate immune activation by reservoir endothelial cells. PLoS Pathogens. 2024. PMID: 39585900.

Donowitz M, Tse C-M, Sarker R, Lin R, Dokladny K, Rawat M, Horwitz I, Ye CY, McNamara G, In J, Kell AM, Guo C, JuiTsai S, Vong T, Karaba A, Singh V, Sachithanandhan J, Pekosz A, Cox A, Bradfute S, Zachos NC, Gould S, Kovbasnjuk O. COVID-19 diarrhea is inflammatory, caused by direct viral effects plus major role of virus-induced cytokines. Cell Mol Gastroenterol Hepatol. 2024. PMID: 39089626.

LaPointe A, Gale Jr. M, Kell AM. Orthohantavirus Replication in the Context of Innate Immunity. Viruses. 2023. PMID: 37243216

Kell AM. Innate immunity to orthohantaviruses: could divergent immune interactions explain host-specific disease outcomes? Journal of Molecular Biology. 2022. PMID: 34487792.

Kaya K, Khalil MI, Fetrow B, Fritz H, Jagadesan P, Bondu V, Ista L,  Chi EY, Schanze KS, Whitten DG, Kell AM. Rapid and Effective Inactivation of SARS-CoV-2 by a Cationic Conjugated Oligomer with Visible Light: Studies of Antiviral Activity in Solutions and on Supports. ACS Applied Materials & Interfaces. 2022. PMID: 35040619.

Zhang Z, Whitten DG, Kell AM. Fluorescent Cellulose Wipe as a New and Sustainable Light-Activated Antibacterial and Antiviral Agent. ACS Materials Letters. 2022. 4, 2, 356–362.

Soveg FW, Schwerk J, Gokhale NS, Cerosaletti K, Smith JR, Pairo-Castineira E, Kell AM, Forero A, Zaver SA, Esser-Nobis K, Roby JA, Hsiang TS, Ozarkar S, Clingan JM, McAnarney ET, Stone AE, Malhotra U, Speake C, Perez J, Balu C, Allenspach EJ, Hyde JL, Menachery VD, Sarkar SN, Woodward JJ, Stetson DB, Baillie JK, Buckner JH, Gale Jr M, Savan R. Endomembrane targeting of human OAS1 p46 augments antiviral activity. Elife. 2021. PMID: 34342578.

Simons P, Rinaldi DA, Bondu V, Kell AM, Bradfute S, Lidke D, Buranda T. Integrin activation is an essential component of SARS-CoV-2 infection. Scientific Reports. 2021. PMID: 34650161.

Monge FA, Jagadesan P, Bondu V, Donabedian PL, Ista L, Chi EY, Schanze KS, Whitten DG, Kell AM. Highly Effective Inactivation of SARS-CoV-2 by Conjugated Polymers and Oligomers. ACS Applied Materials & Interfaces. 2020. PMID: 33267577.

Perkins DJ, Nofchissey R, Ye C, Donart N, Kell AM, Foo-Hurwitz I, Muller T, Bradfute SB. COVID-19 Global Pandemic Planning: Dry heat incubation and ambient temperature fail to consistently inactivate SARS-CoV-2 on N95 respirators. Experimental Biology and Medicine. 2020. PMID: 33342283

Saha B, Chisholm D, Kell AM, Mandell MA. A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5α. PLoS Pathogens. 2020. PMID: 33052966

Kell AM, Hemann E, Turnbull B, Gale Jr M#. RIG-I-like receptor activation drives type I IFN and antiviral signaling to restrict Hantaan orthohantavirus replication. PLoS Pathogens. 2020. PMID: 32330200

Schwerk J, Soveg F, Ryan A, Thomas K, Aarreberg L, Ozarkar S, Forero A, Kell AM, Roby J, So L, Gale Jr. M, Daugherty M, Savan R. RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions. Nature Immunology. 2019. PMID: 31740798

Jarret A, McFarland AP, Horner SM, Kell AM, Schwerk J, Hong M, Badil S, Joslyn RC, Baker DP, Carrington M, Hagedorn CH, Gale Jr. M, Savan R. Hepatitis-C-virus-induced microRNAs dampen interferon mediated antiviral signaling. Nature Medicine. 2016. PMID: 27841874

Hong M, Schwerk J, Lim C, Kell AM, Jarret A, Pangallo J, Loo YM, Liu S, Hagedorn CH, Gale Jr. M, Savan R. Interferon lambda 4 expression is suppressed by the host during viral infection. Journal of Experimental Medicine. 2016. PMID: 27799623

Xu J, Mercado-López X, Grier JT, Kim W, Chuna LF, Irvine EB, Del Toro Duany Y, Kell AM, Hur S, Gale Jr. M, Raj A, López CB. Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I. MBio. 2015. PMID: 26443454

Kell AM, Gale Jr. M. RIG-I in RNA virus recognition. Virology. 2015. PMID: 25749629

Kell AM, Stoddard M, Li H, Marcotrigiano J, Shaw GM, Gale, Jr. M PAMP Recognition of Hepatitis C Virus Transmitted/founder Variants by RIG-I is dependent on U-Core length. Journal of Virology. 2015. PMID: 26311867

Kell AM, Wargo AR, Kurath G. Viral fitness does not correlate with three genotype displacement events involving infectious hematopoietic necrosis virus. Virology. 2014. PMID: 25068402

Kell AM, Wargo AR, Kurath G. The role of virulence for in vivo superinfection fitness of a vertebrate RNA virus. Journal of Virology. 2013. PMID: 23678165

Schiavi A, Torgovnick A, Kell AM, Megalou E, Castelein N, Guccini I, Marzocchella L, Gelino S, Hansen M, Malisan F, Condo’ I, Bei R, Rea S, Braeckman BP, Tavernarakis N, Testi R, Ventura N. Autophagy induction extends lifespan and reduces lipids content in response to frataxin silencing in C. elegans. Experimental Gerontology. 2012. PMID: 23247094

Wargo AR, Kell AM, Scott RJ, Thorgaard GH, Kurath G. Analysis of host genetic diversity and viral entry as sources of between-host variation in viral load. Virus Research. 2012. PMID: 22310066

Kahn NW, Rea SL, Moyle S, Kell AM, Johnson TE. Proteosomal dysfunction activates the transcription factor SKN-1 and produces a selective oxidative stress response in Caenorhabditis elegans. The Biochemical Journal. 2008. PMID: 17714076

Kell AM, Ventura N, Kahn K, and Johnson TE. Activation of SKN-1 by Novel Kinases in Caenorhabditis elegans. Free Radical Biology & Medicine. 2007. PMID: 17964427